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Login to your account Institutional Login Sign In / Register PHYSIOLOGY.ORG Skip main navigation Close Drawer Menu Open Drawer Menu Home Journals AJP-Cell AJP-Endo AJP-GI AJP-Heart AJP-Lung AJP-Regu AJP-Renal AJP (1898-1976) Function J Appl Physiol J Neurophysiol Physiol Genomics Adv Physiol Educ Physiology Physiol Rev PHYSIOL REP COMPR PHYSIOL APSselect All journals This Journal Quick Search anywhere Search all content Search Advanced Search Quick Search in Journals Search all content Search Advanced Search Advanced Search 0 Sign in Skip main navigation Close Drawer Menu Open Drawer Menu Home COLLECTIONS COVID-19 Cross-Journal AJP-CELL AJP-ENDO AJP-GI AJP-HEART AJP-REGU AJP-RENAL JAPPL JN PG ADVANCES PHYSREV APS LEGACY APSSELECT This Month's Selections About INFORMATION For Authors For Reviewers For Librarians For Advertisers For Media/Public For APS Members OTHER PUBLICATIONS Books The Physiologist Magazine ABOUT APS Publications American Physiological Society SUBMIT SUBSCRIBE HELP Skip slideshow Press Release read more Menopausal Changes May Increase Taste for Fat, Drive Weight Gain APS select March selection read more Sex Differences in Fat Taste Responsiveness are Modulated by Estradiol Research Article read more Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21 Research Article read more MOTS-c reduces myostatin and muscle atrophy signaling Review Article read more 100 th Anniversary of the discovery of insulin Perspective: Insulin and Adipose Tissue Fatty Acid Metabolism American Journal of Physiology Endocrinology and Metabolism Journal home Issues Archive of all online content January 1977 March 2021 1970s 1980s 1990s 2000s 2010s 2020s 1977 1978 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 Articles in Press Volume 320, Issue 3 March 2021 Pages E399-E652 Volume 320, Issue 2 February 2021 Pages E179-E398 Volume 320, Issue 1 January 2021 Pages E1-E177 Collections Information For Authors For Reviewers For Librarians For Advertisers For Media/Public For APS Members About About ajpendo Article Types Editor's Bio Editorial Board Submit Subscribe This Journal Quick Search in Journals Search this journal Search Search this journal Journal Menu Home Issues Collections Information About Editor-in-Chief André Marette Information for Authors TOC alerts RSS Feed Twitter Facebook LinkedIn Current issue March 2021; volume 320, issue 3 REVIEWS Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models A systematic review on thyroid organoid models: time-trend and its achievements Hilda Samimi, Rasha Atlasi, Somayeh Parichehreh-Dizaji, Samaneh Khazaei, Mahshid Akhavan Rahnama, Soroush Seifirad, Vahid Haghpanah 2021 Mar 04 : E581-E590 https://doi.org/10.1152/ajpendo.00479.2020 Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions Is nuclear sirtuin SIRT6 a master regulator of immune function? Vinodkumar B. Pillai and Mahesh P. Gupta 2021 Feb 25 : E399-E414 https://doi.org/10.1152/ajpendo.00483.2020 MINI-REVIEWS Browning and Beiging of Adipose Tissue: Its Role in the Regulation of Energy Homeostasis and as a Potential Target for Alleviating Metabolic Diseases An update on brown adipose tissue biology: a discussion of recent findings Rafael C. Gaspar, José R. Pauli, Gerald I. Shulman, Vitor R. Muñoz 2021 Mar 04 : E488-E495 https://doi.org/10.1152/ajpendo.00310.2020 Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions Visceral adipose tissue mesenchymal stromal cells in the intersection of immunology and metabolism Raul German Spallanzani 2021 Mar 04 : E512-E519 https://doi.org/10.1152/ajpendo.00341.2020 See full Table of Contents Editor-in-Chief André Marette Calls for Papers Information for Authors TOC alerts RSS Feed Twitter Facebook LinkedIn Instagram Twitter Twitter Calls for Papers Chronicity in Metabolism Deadline: December 31, 2021 Deciphering the Contribution of the Gastrointestinal Tract on Glucose, Lipid, and Energy Metabolism Deadline: December 31, 2021 Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models Deadline: December 31, 2021 GPCR-Mediated Regulation of Fuel and Energy Metabolism in Peripheral Tissues Deadline: December 31, 2021 Insulin’s First 100 Years — Where Next? Deadline: December 31, 2021 Announcements FlexSubmit Now Available for All Journals 2018 Impact Factors Released for APS Journals Read AJP-Endo research collections Newly published Research Reviews Editorials Articles in Press 8 Mar 2021 DNMT1-mediated lncRNA MEG3 methylation accelerates endothelial-mesenchymal transition in diabetic retinopathy through the PI3K/Akt/mTOR signaling pathway 8 Mar 2021 The prorenin receptor and its soluble form contribute to lipid homeostasis 8 Mar 2021 Prolonged β 2 -adrenergic agonist treatment improves glucose homeostasis in diet-induced obese UCP1 −/− mice 8 Mar 2021 Metabolic flux analysis of branched-chain amino and keto acids (BCAA, BCKA) and β-hydroxy β-methylbutyric acid across multiple organs in the pig 8 Mar 2021 Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in mice 4 Mar 2021 An update on brown adipose tissue biology: a discussion of recent findings 4 Mar 2021 Visceral adipose tissue mesenchymal stromal cells in the intersection of immunology and metabolism 4 Mar 2021 A systematic review on thyroid organoid models: time-trend and its achievements 25 Feb 2021 Is nuclear sirtuin SIRT6 a master regulator of immune function? 10 Jan 2021 The fascinating physiology of insulin: celebrating a centennial hormone 12 Nov 2020 Role of creatine and creatine kinase in UCP1-independent adipocyte thermogenesis 12 Nov 2020 Mechanism of futile creatine cycling in thermogenesis 12 Dec 2016 Quenching the thirst for hunger 8 Mar 2021 The long noncoding RNA TUNAR modulates Wnt signaling and regulates human β-cell proliferation 8 Mar 2021 Transthyretin contributes to insulin resistance and diminishes exercise-induced insulin sensitivity in obese mice by inhibiting AMPK activity in skeletal muscle 8 Mar 2021 Higher protein intake during resistance training does not potentiate strength, but modulates gut microbiota, in middle-aged adults: a randomized control trial 1 Mar 2021 Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms See all Articles in Press Trending research Most read Most cited 2020 Jul 16 Reply to Jakovac: COVID-19, vitamin D, and type I interferon Read more 2021 Feb 22 Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21 Read more 2021 Feb 8 MOTS-c reduces myostatin and muscle atrophy signaling Read more 2021 Feb 1 100 th Anniversary of the discovery of insulin Perspective: Insulin and Adipose Tissue Fatty Acid Metabolism Read more 2021 Feb 3 Impact of prolonged fasting on insulin secretion, insulin action, and hepatic versus whole body insulin secretion disposition indices in healthy young males Read more 26 Apr 2020 COVID-19 pandemic, coronaviruses, and diabetes mellitus 1 Dec 2001 Testosterone dose-response relationships in healthy young men 1 May 2007 EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR 1 Jun 2020 Is there an impact of the COVID-19 pandemic on male fertility? The ACE2 connection 1 Dec 2004 Difference in skeletal muscle function in males vs. females: role of estrogen receptor-β 15 Sep 2014 Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1 26 Apr 2020 COVID-19 pandemi...